Morphine-like peptides in mammalian brain: isolation, structure elucidation, and interactions with the opiate receptor.

Interaction of morphine- and codeine-epoxides with opiate receptor.

19. Pharmacology of Endogenous Opiate-like Peptides*

The presence of endogenous substances which interact with existing cellular receptors has been observed in numerous systems. Steroids express their action by interacting with cytoplasmic receptors in the target tissue. Peptide hormones, e.g., insulin, express their action by interacting with their respective membrane receptors and thus altering the intracellular level of c-AMP. Since it was dem...

Isolation and structure elucidation of a new alkaloid from the Indonesian Blue-Green Alga Arthrospira platensis

A new alkaloid (1) and two known compounds (2 and 3) were isolated from the blue-greenalga Arthrospira platensis. Their structures were determined on the basis of spectroscopic data.According to the obtained data and values in the literature, the compounds were concluded to beeckol.

the past hospitalization and its association with suicide attempts and ideation in patients with mdd and comparison with bmd (depressed type) group

چکیده ندارد.

Identification of the convulsant opiate thebaine in mammalian brain.

The convulsant opiate thebaine, an intermediate of morphine biosynthesis, was purified from bovine brain to homogeneity by gel filtration and high-performance liquid chromatography (HPLC) monitored by a radioimmunoassay. The immunoreactive material behaved identically to standard thebaine in two HPLC systems and was confirmed to be thebaine by combined gas chromatography/mass spectrometry. To o...